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Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A(2B) Receptor Binding Affinity

The G protein-coupled adenosine A(2B) receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer. Therefore, the adenosine A(2B) receptor is currently in focus as a novel target for cancer therapy...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Lindemann, Marcel, Dukic-Stefanovic, Sladjana, Hinz, Sonja, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Juhl, Cathleen, Steinbach, Jörg, Brust, Peter, Müller, Christa E., Wenzel, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161391/
https://ncbi.nlm.nih.gov/pubmed/34069548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050485
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