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Synthesis of Novel Fluorinated Xanthine Derivatives with High Adenosine A(2B) Receptor Binding Affinity

The G protein-coupled adenosine A(2B) receptor is suggested to be involved in various pathological processes accompanied by increased levels of adenosine as found in inflammation, hypoxia, and cancer. Therefore, the adenosine A(2B) receptor is currently in focus as a novel target for cancer therapy...

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Détails bibliographiques
Publié dans:Pharmaceuticals (Basel)
Auteurs principaux: Lindemann, Marcel, Dukic-Stefanovic, Sladjana, Hinz, Sonja, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Juhl, Cathleen, Steinbach, Jörg, Brust, Peter, Müller, Christa E., Wenzel, Barbara
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8161391/
https://ncbi.nlm.nih.gov/pubmed/34069548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14050485
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