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Growth Inhibitory Effects of Ester Derivatives of Menahydroquinone-4, the Reduced Form of Vitamin K(2(20)), on All-Trans Retinoic Acid-Resistant HL60 Cell Line
The first-choice drug for acute promyelocytic leukemia (APL), all-trans retinoic acid (ATRA), frequently causes drug-resistance and some adverse effects. Thus, an effective and safe agent for ATRA-resistant APL is needed. Menaquinone-4 (MK-4, vitamin K(2(20))), used for osteoporosis treatment, does...
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| Publicado no: | Pharmaceutics |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8161027/ https://ncbi.nlm.nih.gov/pubmed/34065416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13050758 |
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