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GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells
Diabetes is a metabolic syndrome rooted in impaired insulin and/or glucagon secretory responses within the pancreatic islets of Langerhans (islets). Insulin secretion is primarily regulated by two key factors: glucose-mediated ATP production and G-protein coupled receptors (GPCRs) signaling. GPCR ki...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8159944/ https://ncbi.nlm.nih.gov/pubmed/34045505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90253-z |
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