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Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets

Chronic exposure to inorganic arsenic (iAs), a common drinking water and food contaminant, has been associated with an increased risk of type 2 diabetes in population studies worldwide. Several mechanisms underlying the diabetogenic effects of iAs have been proposed through laboratory investigations...

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Библиографические подробности
Опубликовано в: :Arch Toxicol
Главные авторы: Huang, Madelyn, Douillet, Christelle, Stýblo, Miroslav
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245054/
https://ncbi.nlm.nih.gov/pubmed/31332465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02526-2
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