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Exposures to arsenite and methylarsonite produce insulin resistance and impair insulin-dependent glycogen metabolism in hepatocytes

Environmental exposure to inorganic arsenic (iAs) has been shown to disturb glucose homeostasis, leading to diabetes. Previous laboratory studies have suggested several mechanisms that may underlie the diabetogenic effects of iAs exposure, including (i) inhibition of insulin signaling (leading to in...

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Vydáno v:Arch Toxicol
Hlavní autoři: Zhang, Chongben, Fennel, Emily M. J., Douillet, Christelle, Stýblo, Miroslav
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611171/
https://ncbi.nlm.nih.gov/pubmed/28952001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2076-9
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