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Knockout of arsenic (+3 oxidation state) methyltransferase is associated with adverse metabolic phenotype in mice: The role of sex and arsenic exposure

Susceptibility to toxic effects of inorganic arsenic (iAs) depends, in part, on efficiency of iAs methylation by arsenic (+3 oxidation state) methyltransferase (AS3MT). As3mt-knockout (KO) mice that cannot efficiently methylate iAs represent an ideal model to study the association between iAs metabo...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Douillet, Christelle, Huang, Madelyn C., Saunders, R. Jesse, Dover, Ellen N., Zhang, Chongben, Stýblo, Miroslav
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432424/
https://ncbi.nlm.nih.gov/pubmed/27847981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1890-9
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