Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: Effect of sex and arsenic exposure

Arsenic (+3 oxidation state) methyltransferase (As3mt) is the key enzyme in the pathway for methylation of inorganic arsenic (iAs). Altered As3mt expression and AS3MT polymorphism have been linked to changes in iAs metabolism and in susceptibility to iAs toxicity in laboratory models and in humans....

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Udgivet i:Arch Toxicol
Main Authors: Huang, Madelyn C., Douillet, Christelle, Su, Mingming, Zhou, Kejun, Wu, Tao, Chen, Wenlian, Galanko, Joseph A., Drobná, Zuzana, Saunders, R. Jesse, Martin, Elizabeth, Fry, Rebecca C., Jia, Wei, Stýblo, Miroslav
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987274/
https://ncbi.nlm.nih.gov/pubmed/26883664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1676-0
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