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Knockout of arsenic (+3 oxidation state) methyltransferase results in sex-dependent changes in phosphatidylcholine metabolism in mice

Arsenic (+3 oxidation state) methyltransferase is the key enzyme in the methylation pathway for inorganic arsenic. We have recently shown that As3mt knockout (KO) has a profound effect on metabolomic profiles in mice. Phosphatidylcholine species (PCs) were the largest group of metabolites altered in...

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Publicat a:Arch Toxicol
Autors principals: Huang, Madelyn C., Douillet, Christelle C., Stýblo, Miroslav
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358322/
https://ncbi.nlm.nih.gov/pubmed/27591999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1844-2
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