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Arsenite and its trivalent methylated metabolites inhibit glucose-stimulated calcium influx and insulin secretion in murine pancreatic islets

Chronic exposure to inorganic arsenic (iAs), a common drinking water and food contaminant, has been associated with an increased risk of type 2 diabetes in population studies worldwide. Several mechanisms underlying the diabetogenic effects of iAs have been proposed through laboratory investigations...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Huang, Madelyn, Douillet, Christelle, Stýblo, Miroslav
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245054/
https://ncbi.nlm.nih.gov/pubmed/31332465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-019-02526-2
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