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Effect of intracellular alkalinization on pancreatic islet calcium uptake and insulin secretion.

Microdissected beta-cell-rich pancreatic islets of ob/ob mice were used in studies of the relationship between intracellular pH (pHi) and 45Ca2+ uptake and insulin release. Stepwise increases in extracellular pH (pHo) from 6.80 to 8.00 resulted in a parallel, although less pronounced, elevation of p...

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Detalhes bibliográficos
Main Authors: Lindström, P, Sehlin, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147260/
https://ncbi.nlm.nih.gov/pubmed/3541920
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