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GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells

Diabetes is a metabolic syndrome rooted in impaired insulin and/or glucagon secretory responses within the pancreatic islets of Langerhans (islets). Insulin secretion is primarily regulated by two key factors: glucose-mediated ATP production and G-protein coupled receptors (GPCRs) signaling. GPCR ki...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Snyder, Jonathan, Lackey, Atreju I, Brown, G. Schuyler, Diaz, Melisa, Yuzhen, Tian, Sato, Priscila Y.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159944/
https://ncbi.nlm.nih.gov/pubmed/34045505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90253-z
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