PGC-1α Protects against Hepatic Ischemia Reperfusion Injury by Activating PPARα and PPARγ and Regulating ROS Production

Peroxisome proliferator-activated receptors (PPARs) α and γ have been shown to be protective in hepatic ischemia/reperfusion (I/R) injury. However, the precise role of PPARγ coactivator-1α (PGC-1α), which can coactivate both of these receptors, in hepatic I/R injury, remains largely unknown. This st...

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Dades bibliogràfiques
Publicat a:Oxid Med Cell Longev
Autors principals: Wang, Chaoqun, Li, Zihao, Zhao, Baolei, Wu, Yaohua, Fu, Yao, Kang, Kai, Li, Yao, Dong, Liqian, Li, Xiaozhuang, Zhang, Bao, Wu, Huibo, Shen, Benqiang, Xu, Yanan, Pan, Shangha, Jiang, Hongchi, Wang, Dawei, Ma, Yong
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159639/
https://ncbi.nlm.nih.gov/pubmed/34104311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6677955
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