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TNF and IL-1 Decrease RXRα, PPARα, PPARγ, LXRα, and the Coactivators SRC-1, PGC-1α, and PGC-1β in Liver Cells
During the acute phase response (APR), cytokines induce marked alterations in lipid metabolism including an increase in serum triglycerides, a decrease in hepatic fatty acid oxidation, a decrease in bile acid synthesis, and a decrease in HDL. Here we demonstrate that TNF and IL-1, but not IL-6, decr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700944/ https://ncbi.nlm.nih.gov/pubmed/17224343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2006.10.007 |
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