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Chemical synthesis of human syndecan-4 glycopeptide bearing O-, N-sulfation and multiple aspartic acids for probing impacts of the glycan chain and the core peptide on biological functions

Proteoglycans are a family of complex glycoproteins with glycosaminoglycan chains such as heparan sulfate (HS) attached to the core protein backbone. Due to the high structural heterogeneity of HS in nature, it is challenging to decipher the respective roles of the HS chain and the core protein on p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chem Sci
Egile Nagusiak: Yang, Weizhun, Eken, Yigitcan, Zhang, Jicheng, Cole, Logan Emerson, Ramadan, Sherif, Xu, Yongmei, Zhang, Zeren, Liu, Jian, Wilson, Angela K., Huang, Xuefei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Royal Society of Chemistry 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159385/
https://ncbi.nlm.nih.gov/pubmed/34094105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc01140a
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