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Homoserine as an Aspartic Acid Precursor for Synthesis of Proteoglycan Glycopeptide Containing Aspartic Acid and Sulfated Glycan Chain

Among many hurdles in synthesizing proteoglycan glycopeptides, one challenge is the incorporation of aspartic acid in the peptide backbone and acid sensitive O-sulfated glycan chains. To overcome this, a new strategy was developed utilizing homoserine as an aspartic acid precursor. The conversion of...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Yang, Weizhun, Ramadan, Sherif, Yang, Bo, Yoshida, Keisuke, Huang, Xuefei
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215661/
https://ncbi.nlm.nih.gov/pubmed/27809505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b02441
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