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Synthesis of O‑Sulfated Human Syndecan-1-like Glyco-polypeptides by Incorporating Peptide Ligation and O‑Sulfated Glycopeptide Cassette Strategies

A successful synthesis of O-sulfated syndecan-1-like (Q23–E120) glyco-polypeptide was accomplished. The synthesis features the integration of an O-sulfated carbohydrate-bearing glycopeptide cassette with efficient protein ligation strategies, overcoming the acid lability of carbohydrate sulfates as...

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Vydáno v:Org Lett
Hlavní autoři: Li, Tianlu, Yang, Weizhun, Ramadan, Sherif, Huang, Xuefei
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517924/
https://ncbi.nlm.nih.gov/pubmed/32806172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c02243
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