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Chemoenzymatic synthesis of glycopeptides bearing rare N-glycan sequences with or without bisecting GlcNAc

N-Linked glycopeptides have highly diverse structures in nature. Herein, we describe the first synthesis of rare multi-antennary N-glycan bearing glycan chains on 6-OH of both α1,6- and α1,3-linked mannose arms. To expedite divergent generation of N-glycan structures, four orthogonal protective grou...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Yang, Weizhun, Ramadan, Sherif, Orwenyo, Jared, Kakeshpour, Tayeb, Diaz, Thomas, Eken, Yigitcan, Sanda, Miloslav, Jackson, James E., Wilson, Angela K., Huang, Xuefei
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6240809/
https://ncbi.nlm.nih.gov/pubmed/30542567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02457j
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