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Mechanisms of Beta-Cell Apoptosis in Type 2 Diabetes-Prone Situations and Potential Protection by GLP-1-Based Therapies

Type 2 diabetes (T2D) is characterized by chronic hyperglycemia secondary to the decline of functional beta-cells and is usually accompanied by a reduced sensitivity to insulin. Whereas altered beta-cell function plays a key role in T2D onset, a decreased beta-cell mass was also reported to contribu...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Costes, Safia, Bertrand, Gyslaine, Ravier, Magalie A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157542/
https://ncbi.nlm.nih.gov/pubmed/34069914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105303
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