GLP-1–oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice

AIMS/HYPOTHESIS: Oestrogens have previously been shown to exert beta cell protective, glucose-lowering effects in mouse models. Therefore, the recent development of a glucagon-like peptide-1 (GLP-1)–oestrogen conjugate, which targets oestrogen into cells expressing GLP-1 receptors, offers an opportu...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Diabetologia
Egile Nagusiak: Schwenk, Robert W., Baumeier, Christian, Finan, Brian, Kluth, Oliver, Brauer, Christine, Joost, Hans-Georg, DiMarchi, Richard D., Tschöp, Matthias H., Schürmann, Annette
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320309/
https://ncbi.nlm.nih.gov/pubmed/25527001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3478-3
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