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Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice

OBJECTIVE: Obesity is a major health threat that affects men and women equally. Despite this fact, weight-loss potential of pharmacotherapies is typically first evaluated in male mouse models of diet-induced obesity (DIO). To address this disparity we herein determined whether a monomeric peptide wi...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Jall, Sigrid, Sachs, Stephan, Clemmensen, Christoffer, Finan, Brian, Neff, Frauke, DiMarchi, Richard D., Tschöp, Matthias H., Müller, Timo D., Hofmann, Susanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404097/
https://ncbi.nlm.nih.gov/pubmed/28462078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.02.002
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