A Phase I proof-of-concept and safety trial of sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage

OBJECTIVE: Studies show that phosphodiesterase-V (PDE-V) inhibition reduces cerebral vasospasm (CVS) and improves outcomes after experimental subarachnoid hemorrhage (SAH). This study was performed to investigate the safety and effect of sildenafil (an FDA-approved PDE-V inhibitor) on angiographic C...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosurg
Hoofdauteurs: Washington, Chad W., Derdeyn, Colin P., Dhar, Rajat, Arias, Eric J., Chicoine, Michael R., Cross, DeWitte T., Dacey, Ralph G., Han, Byung Hee, Moran, Christopher J., Rich, Keith M., Vellimana, Ananth K., Zipfel, Gregory J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157481/
https://ncbi.nlm.nih.gov/pubmed/26314998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2015.2.JNS142752
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items