Fc-binding antibody-recruiting molecules exploit endogenous antibodies for anti-tumor immune responses

Redirecting endogenous antibodies in the bloodstream to tumor cells using synthetic molecules is a promising approach to trigger anti-tumor immune responses. However, current molecular designs only enable the use of a small fraction of endogenous antibodies, limiting the therapeutic potential. Here,...

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Vydáno v:Chem Sci
Hlavní autoři: Sasaki, Koichi, Harada, Minori, Miyashita, Yoshiki, Tagawa, Hiroshi, Kishimura, Akihiro, Mori, Takeshi, Katayama, Yoshiki
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society of Chemistry 2020
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157400/
https://ncbi.nlm.nih.gov/pubmed/34122826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc00017e
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