Encapsulation of a nitric oxide donor into a liposome to boost the enhanced permeation and retention (EPR) effect

We propose a method to improve the enhanced permeability and retention (EPR) effect of nanomedicines based on tumor-specific vasodilation using a nitric oxide (NO) donor-containing liposome. NONOate, a typical NO donor, was incorporated into a PEGylated liposome to retard the protonation-induced rel...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Tahara, Yu, Yoshikawa, Takuma, Sato, Hikari, Mori, Yukina, Zahangir, Md Hosain, Kishimura, Akihiro, Mori, Takeshi, Katayama, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072363/
https://ncbi.nlm.nih.gov/pubmed/30108759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00614k
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