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Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect

Tumor vasculature is characterized by a variety of abnormalities including irregular architecture, poor lymphatic drainage, and the upregulation of factors that increase the paracellular permeability. The increased permeability is important in mediating the uptake of an intravenously administered dr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wong, Andrew D., Ye, Mao, Ulmschneider, Martin B., Searson, Peter C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418820/
https://ncbi.nlm.nih.gov/pubmed/25938565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123461
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