Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts

Ascorbic acid (AA) is widely used in cosmetic formulations due to its antioxidant property and ability to increase collagen synthesis. Here, we encapsulated AA in vesicles with different lipid compositions. Negative liposome charge favored AA skin retention, with accumulation of 37 ± 12 and 74 ± 23 ...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maione-Silva, Lorena, de Castro, Elisandra Gava, Nascimento, Thais Leite, Cintra, Emílio Ramos, Moreira, Larissa Cleres, Cintra, Bertilha Alves Santana, Valadares, Marize Campos, Lima, Eliana Martins
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345870/
https://ncbi.nlm.nih.gov/pubmed/30679479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36682-9
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