Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts

Ascorbic acid (AA) is widely used in cosmetic formulations due to its antioxidant property and ability to increase collagen synthesis. Here, we encapsulated AA in vesicles with different lipid compositions. Negative liposome charge favored AA skin retention, with accumulation of 37 ± 12 and 74 ± 23 ...

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Pubblicato in:Sci Rep
Autori principali: Maione-Silva, Lorena, de Castro, Elisandra Gava, Nascimento, Thais Leite, Cintra, Emílio Ramos, Moreira, Larissa Cleres, Cintra, Bertilha Alves Santana, Valadares, Marize Campos, Lima, Eliana Martins
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345870/
https://ncbi.nlm.nih.gov/pubmed/30679479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36682-9
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