Synthesis and biological evaluation of a monocyclic Fc-binding antibody-recruiting molecule for cancer immunotherapy

Antibody-recruiting molecules (ARMs) are bispecific molecules composed of an antibody-binding motif and a target-binding motif that redirect endogenous antibodies to target cells to elicit immune responses. To enhance the translational potential of ARMs, it is crucial to design antibody/target-bindi...

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Detalles Bibliográficos
Publicado en:RSC Med Chem
Autores principales: Sasaki, Koichi, Muguruma, Kyohei, Osawa, Rento, Fukuda, Akane, Taniguchi, Atsuhiko, Kishimura, Akihiro, Hayashi, Yoshio, Mori, Takeshi, Katayama, Yoshiki
Formato: Artigo
Lenguaje:Inglês
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130626/
https://ncbi.nlm.nih.gov/pubmed/34046623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00337a
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