Development of Potent Myostatin Inhibitory Peptides through Hydrophobic Residue-Directed Structural Modification

[Image: see text] Myostatin, a negative regulator of skeletal muscle growth, is a promising target for treating muscle atrophic disorders. Recently, we discovered a minimal myostatin inhibitor 1 (WRQNTRYSRIEAIKIQILSKLRL-amide) derived from positions 21–43 of the mouse myostatin prodomain. We previou...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Takayama, Kentaro, Rentier, Cédric, Asari, Tomo, Nakamura, Akari, Saga, Yusuke, Shimada, Takahiro, Nirasawa, Kei, Sasaki, Eri, Muguruma, Kyohei, Taguchi, Akihiro, Taniguchi, Atsuhiko, Negishi, Yoichi, Hayashi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512132/
https://ncbi.nlm.nih.gov/pubmed/28740611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00168
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados