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Development of Potent Myostatin Inhibitory Peptides through Hydrophobic Residue-Directed Structural Modification
[Image: see text] Myostatin, a negative regulator of skeletal muscle growth, is a promising target for treating muscle atrophic disorders. Recently, we discovered a minimal myostatin inhibitor 1 (WRQNTRYSRIEAIKIQILSKLRL-amide) derived from positions 21–43 of the mouse myostatin prodomain. We previou...
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| Udgivet i: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2017
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512132/ https://ncbi.nlm.nih.gov/pubmed/28740611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00168 |
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