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Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of (11)C-Labeled ALK2 Inhibitors
[Image: see text] Mutations in the gene encoding activin receptor-like kinase 2 (ALK2) are implicated in the pathophysiology of a pediatric brainstem cancer, diffuse intrinsic pontine glioma (DIPG). Inhibitors of ALK2 that cross the blood–brain barrier have been proposed as a method of treatment for...
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| Publicado no: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2021
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8155239/ https://ncbi.nlm.nih.gov/pubmed/34055235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.1c00127 |
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