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Radiofluorination of oxazole-carboxamides for preclinical PET neuroimaging of GSK-3

Glycogen synthase kinase 3 (GSK-3) is an enzyme that is dysregulated in oncology neurodegeneration, neuroinflammation and several mental health illnesses. As such, GSK-3 is a long-sought after target for positron emission tomography (PET) imaging and therapeutic intervention. Herein, we report on th...

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Detalhes bibliográficos
Publicado no:J Fluor Chem
Main Authors: Varlow, Cassis, Mossine, Andrew V., Bernard-Gauthier, Vadim, Scott, Peter J. H., Vasdev, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034590/
https://ncbi.nlm.nih.gov/pubmed/33840834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jfluchem.2021.109760
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