The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

RNA splicing, transcription and the DNA damage response are intriguingly linked in mammals but the underlying mechanisms remain poorly understood. Using an in vivo biotinylation tagging approach in mice, we show that the splicing factor XAB2 interacts with the core spliceosome and that it binds to s...

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Publicado no:Nat Commun
Main Authors: Goulielmaki, Evi, Tsekrekou, Maria, Batsiotos, Nikos, Ascensão-Ferreira, Mariana, Ledaki, Eleftheria, Stratigi, Kalliopi, Chatzinikolaou, Georgia, Topalis, Pantelis, Kosteas, Theodore, Altmüller, Janine, Demmers, Jeroen A., Barbosa-Morais, Nuno L., Garinis, George A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155215/
https://ncbi.nlm.nih.gov/pubmed/34039990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23505-1
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