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The ERCC1 and ERCC4 (XPF) genes and gene products

The ERCC1 and ERCC4 genes encode the two subunits of the ERCC1–XPF nuclease. This enzyme plays an important role in repair of DNA damage and in maintaining genomic stability. ERCC1–XPF nuclease nicks DNA specifically at junctions between double-stranded and single-stranded DNA, when the single-stran...

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Publicat a:Gene
Autors principals: Manandhar, Mandira, Boulware, Karen S., Wood, Richard D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536074/
https://ncbi.nlm.nih.gov/pubmed/26074087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.06.026
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