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The ERCC1 and ERCC4 (XPF) genes and gene products
The ERCC1 and ERCC4 genes encode the two subunits of the ERCC1–XPF nuclease. This enzyme plays an important role in repair of DNA damage and in maintaining genomic stability. ERCC1–XPF nuclease nicks DNA specifically at junctions between double-stranded and single-stranded DNA, when the single-stran...
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| Publié dans: | Gene |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536074/ https://ncbi.nlm.nih.gov/pubmed/26074087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2015.06.026 |
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