The splicing factor XAB2 interacts with ERCC1-XPF and XPG for R-loop processing

RNA splicing, transcription and the DNA damage response are intriguingly linked in mammals but the underlying mechanisms remain poorly understood. Using an in vivo biotinylation tagging approach in mice, we show that the splicing factor XAB2 interacts with the core spliceosome and that it binds to s...

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Pubblicato in:Nat Commun
Autori principali: Goulielmaki, Evi, Tsekrekou, Maria, Batsiotos, Nikos, Ascensão-Ferreira, Mariana, Ledaki, Eleftheria, Stratigi, Kalliopi, Chatzinikolaou, Georgia, Topalis, Pantelis, Kosteas, Theodore, Altmüller, Janine, Demmers, Jeroen A., Barbosa-Morais, Nuno L., Garinis, George A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155215/
https://ncbi.nlm.nih.gov/pubmed/34039990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23505-1
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