Targeting the epichaperome as an effective precision medicine approach in a novel PML-SYK fusion acute myeloid leukemia

The epichaperome is a new cancer target composed of hyperconnected networks of chaperome members that facilitate cell survival. Cancers with an altered chaperone configuration may be susceptible to epichaperome inhibitors. We developed a flow cytometry-based assay for evaluation and monitoring of ep...

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Xehetasun bibliografikoak
Argitaratua izan da:NPJ Precis Oncol
Egile Nagusiak: Sugita, Mayumi, Wilkes, David C., Bareja, Rohan, Eng, Kenneth W., Nataraj, Sarah, Jimenez-Flores, Reyna A., Yan, LunBiao, De Leon, Jeanne Pauline, Croyle, Jaclyn A., Kaner, Justin, Merugu, Swathi, Sharma, Sahil, MacDonald, Theresa Y., Noorzad, Zohal, Panchal, Palak, Pancirer, Danielle, Cheng, Shuhua, Xiang, Jenny Z., Olson, Luke, Van Besien, Koen, Rickman, David S., Mathew, Susan, Tam, Wayne, Rubin, Mark A., Beltran, Himisha, Sboner, Andrea, Hassane, Duane C., Chiosis, Gabriela, Elemento, Olivier, Roboz, Gail J., Mosquera, Juan Miguel, Guzman, Monica L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2021
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155064/
https://ncbi.nlm.nih.gov/pubmed/34040147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00183-2
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