Paradigms for precision medicine in epichaperome cancer therapy

Alterations in protein-protein interaction networks are at the core of malignant transformation but have yet to be translated into appropriate diagnostic tools. We make use of the kinetic selectivity properties of an imaging probe to visualize and measure the epichaperome, a pathologic protein-prote...

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Vydáno v:Cancer Cell
Hlavní autoři: Pillarsetty, Nagavarakishore, Jhaveri, Komal, Taldone, Tony, Caldas-Lopes, Eloisi, Punzalan, Blesida, Joshi, Suhasini, Bolaender, Alexander, Uddin, Mohammad M., Rodina, Anna, Yan, Pengrong, Ku, Anson, Ku, Thomas, Shah, Smit K., Lyashchenko, Serge, Burnazi, Eva, Wang, Tai, Lecomte, Nicolas, Janjigian, Yelena, Younes, Anas, Batlevi, Connie W., Guzman, Monica L., Roboz, Gail J., Koziorowski, Jacek, Zanzonico, Pat, Alpaugh, Mary L., Corben, Adriana, Modi, Shanu, Norton, Larry, Larson, Steven M., Lewis, Jason S., Chiosis, Gabriela, Gerecitano, John F., Dunphy, Mark P.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996250/
https://ncbi.nlm.nih.gov/pubmed/31668946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2019.09.007
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