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TAPBPR promotes antigen loading on MHC-I molecules using a peptide trap
Chaperones Tapasin and TAP-binding protein related (TAPBPR) perform the important functions of stabilizing nascent MHC-I molecules (chaperoning) and selecting high-affinity peptides in the MHC-I groove (editing). While X-ray and cryo-EM snapshots of MHC-I in complex with TAPBPR and Tapasin, respecti...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8154891/ https://ncbi.nlm.nih.gov/pubmed/34039964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23225-6 |
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