Molecular determinants of chaperone interactions on MHC-I for folding and antigen repertoire selection

The interplay between a highly polymorphic set of MHC-I alleles and molecular chaperones shapes the repertoire of peptide antigens displayed on the cell surface for T cell surveillance. Here, we demonstrate that the molecular chaperone TAP-binding protein related (TAPBPR) associates with a broad ran...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McShan, Andrew C., Devlin, Christine A., Overall, Sarah A., Park, Jihye, Toor, Jugmohit S., Moschidi, Danai, Flores-Solis, David, Choi, Hannah, Tripathi, Sarvind, Procko, Erik, Sgourakis, Nikolaos G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6926029/
https://ncbi.nlm.nih.gov/pubmed/31796585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1915562116
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