Mechanistic Differences of Activation of Rac1(P29S) and Rac1(A159V)

[Image: see text] Rac1 is a small GTPase that plays key roles in actin reorganization, cell motility, and cell survival/growth as well as in various cancer types and neurodegenerative diseases. Similar to other Ras superfamily GTPases, Rac1 switches between active GTP-bound and inactive GDP-bound st...

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Bibliografski detalji
Izdano u:J Phys Chem B
Glavni autori: Senyuz, Simge, Jang, Hyunbum, Nussinov, Ruth, Keskin, Ozlem, Gursoy, Attila
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2021
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154616/
https://ncbi.nlm.nih.gov/pubmed/33848152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.1c00883
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