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A Plug-and-Play Platform for the Formation of Trifunctional Cysteine Bioconjugates that also Offers Control over Thiol Cleavability

[Image: see text] Linkers that enable the site-selective synthesis of chemically modified proteins are of great interest to the field of chemical biology. Homogenous bioconjugates often show advantageous pharmacokinetic profiles and consequently increased efficacy in vivo. Cysteine residues have bee...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Bioconjug Chem
मुख्य लेखकों: Bahou, Calise, Szijj, Peter A., Spears, Richard J., Wall, Archie, Javaid, Faiza, Sattikar, Afrah, Love, Elizabeth A., Baker, James R., Chudasama, Vijay
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Chemical Society 2021
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154211/
https://ncbi.nlm.nih.gov/pubmed/33710874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.1c00057
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