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Evaluation of the Preclinical Efficacy of Lurbinectedin in Malignant Pleural Mesothelioma
SIMPLE SUMMARY: The marine drug lurbinectedin revealed an unprecedented efficacy against patient-derived malignant pleural mesothelioma cells, regardless of the histological type and the BAP1 mutation status. By inducing strong DNA damages, it dramatically arrested cell cycle progression and induced...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8151304/ https://ncbi.nlm.nih.gov/pubmed/34066159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102332 |
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