Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment

Systemic treatment of malignant pleural mesothelioma (MPM) is moderately active for the intrinsic pharmacological resistance of MPM cell and its ability to induce an immune suppressive environment. Here we showed that the expression of bromodomain (BRD) proteins BRD2, BRD4 and BRD9 was significantly...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Riganti, Chiara, Lingua, Marcello Francesco, Salaroglio, Iris Chiara, Falcomatà, Chiara, Righi, Luisella, Morena, Deborah, Picca, Francesca, Oddo, Daniele, Kopecka, Joanna, Pradotto, Monica, Libener, Roberta, Orecchia, Sara, Bironzo, Paolo, Comunanza, Valentina, Bussolino, Federico, Novello, Silvia, Scagliotti, Giorgio Vittorio, Di Nicolantonio, Federica, Taulli, Riccardo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790353/
https://ncbi.nlm.nih.gov/pubmed/29399399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1398874
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