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Clinical and Molecular Features of Epidermal Growth Factor Receptor (EGFR) Mutation Positive Non-Small-Cell Lung Cancer (NSCLC) Patients Treated with Tyrosine Kinase Inhibitors (TKIs): Predictive and Prognostic Role of Co-Mutations

SIMPLE SUMMARY: Co-mutations may affect EGFR-TKIs efficacy in advanced EGFR mutated NSCLC and could be associated with worse prognosis. Using a clinical next-generation sequencing (NGS) panel we retrospectively assessed the impact of co-alterations in 106 consecutive patients treated with front-line...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Cancers (Basel)
المؤلفون الرئيسيون:	Bironzo, Paolo, Reale, Maria Lucia, Sperone, Tessa, Tabbò, Fabrizio, Caglio, Andrea, Listì, Angela, Passiglia, Francesco, Di Maio, Massimo, Righi, Luisella, Bussolino, Federico, Scagliotti, Giorgio V., Novello, Silvia
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI 2021
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8156829/ https://ncbi.nlm.nih.gov/pubmed/34067823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102425
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Clinical and Molecular Features of Epidermal Growth Factor Receptor (EGFR) Mutation Positive Non-Small-Cell Lung Cancer (NSCLC) Patients Treated with Tyrosine Kinase Inhibitors (TKIs): Predictive and Prognostic Role of Co-Mutations

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