Clinical and Molecular Features of Epidermal Growth Factor Receptor (EGFR) Mutation Positive Non-Small-Cell Lung Cancer (NSCLC) Patients Treated with Tyrosine Kinase Inhibitors (TKIs): Predictive and Prognostic Role of Co-Mutations

SIMPLE SUMMARY: Co-mutations may affect EGFR-TKIs efficacy in advanced EGFR mutated NSCLC and could be associated with worse prognosis. Using a clinical next-generation sequencing (NGS) panel we retrospectively assessed the impact of co-alterations in 106 consecutive patients treated with front-line...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Bironzo, Paolo, Reale, Maria Lucia, Sperone, Tessa, Tabbò, Fabrizio, Caglio, Andrea, Listì, Angela, Passiglia, Francesco, Di Maio, Massimo, Righi, Luisella, Bussolino, Federico, Scagliotti, Giorgio V., Novello, Silvia
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8156829/
https://ncbi.nlm.nih.gov/pubmed/34067823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13102425
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