Computational Study on Selective PDE9 Inhibitors on PDE9-Mg/Mg, PDE9-Zn/Mg, and PDE9-Zn/Zn Systems

PDE9 inhibitors have been studied to validate their potential to treat diabetes, neurodegenerative disorders, cardiovascular diseases, and erectile dysfunction. In this report, we have selected highly potent previously reported selective PDE9 inhibitors BAY73-6691R, BAY73-6691S, 28r, 28s, 3r, 3s, PF...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Sivakumar, Dakshinamurthy, Mudedla, Sathishkumar, Jang, Seonghun, Kim, Hyunjun, Park, Hyunjin, Choi, Yonwon, Oh, Joongyo, Wu, Sangwook
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151263/
https://ncbi.nlm.nih.gov/pubmed/34068780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11050709
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