Reversal of neurobehavioral social deficits in dystrophic mice using inhibitors of phosphodiesterases PDE5A and PDE9A

Duchenne muscular dystrophy is caused by mutations in the DYSTROPHIN gene. Although primarily associated with muscle wasting, a significant portion of patients (approximately 25%) are also diagnosed with autism spectrum disorder. We describe social behavioral deficits in dystrophin-deficient mice an...

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書目詳細資料
發表在:Transl Psychiatry
Main Authors: Alexander, M S, Gasperini, M J, Tsai, P T, Gibbs, D E, Spinazzola, J M, Marshall, J L, Feyder, M J, Pletcher, M T, Chekler, E L P, Morris, C A, Sahin, M, Harms, J F, Schmidt, C J, Kleiman, R J, Kunkel, L M
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048211/
https://ncbi.nlm.nih.gov/pubmed/27676442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.174
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