Identification of cytosolic phosphodiesterases in the erythrocyte: A possible role for PDE5

BACKGROUND: Within erythrocytes (RBCs), cAMP levels are regulated by phosphodiesterases (PDEs). Increases in cAMP and ATP release associated with activation of β-adrenergic receptors (βARs) and prostacyclin receptors (IPRs) are regulated by PDEs 2, 4 and PDE 3, respectively. Here we establish the pr...

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Hlavní autoři: Adderley, Shaquria P., Thuet, Kelly M., Sridharan, Meera, Bowles, Elizabeth A., Stephenson, Alan H., Ellsworth, Mary L., Sprague, Randy S.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2011
Témata:
Clinical Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366467/
https://ncbi.nlm.nih.gov/pubmed/21525805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.881763
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