Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans

Activation of the G protein G(s) results in increases in cAMP, a necessary step in the pathway for ATP release from rabbit and human erythrocytes. In all cells, the level of cAMP is the product of its synthesis by adenylyl cyclase and its hydrolysis by phosphodiesterases (PDEs). Both iloprost (Ilo),...

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Bibliografiske detaljer
Main Authors: Adderley, Shaquria P., Dufaux, Eileen A., Sridharan, Meera, Bowles, Elizabeth A., Hanson, Madelyn S., Stephenson, Alan H., Ellsworth, Mary L., Sprague, Randy S.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685344/
https://ncbi.nlm.nih.gov/pubmed/19252089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01226.2008
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