JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration

The mechanisms contributing to excessive fibronectin in preeclampsia, a pregnancy-related disorder, remain unknown. Herein, we investigated the role of JMJD6, an O(2)- and Fe(2+)-dependent enzyme, in mediating placental fibronectin processing and function. MALDI-TOF identified fibronectin as a novel...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Alahari, Sruthi, Farrell, Abby, Ermini, Leonardo, Park, Chanho, Sallais, Julien, Roberts, Sarah, Gillmore, Taylor, Litvack, Michael, Post, Martin, Caniggia, Isabella
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149756/
https://ncbi.nlm.nih.gov/pubmed/34055782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.652607
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi